| From | Distance | Miles | Time |
| Panama | (Kms) | hour:min | |
| Tocumen | 27 | 17 | 00:30 |
| Chepo | 57 | 35 | 01:00 |
| Colón | 80 | 49 | 01:15 |
| Sabanitas | 68 | 42 | 01:00 |
| Portobelo | 105 | 65 | 01:40 |
| Arraiján | 13 | 8 | 00:12 |
| Chorrera | 33 | 20 | 00:40 |
| Capira | 54 | 34 | 00:55 |
| Bejuco | 75 | 46 | 01:10 |
| Chame | 76 | 48 | 01:15 |
| San Carlos | 93 | 58 | 01:35 |
| El Valle | 126 | 78 | 02:05 |
| Santa Clara | 118 | 73 | 01:55 |
| Río Hato | 123 | 77 | 02:00 |
| Antón | 135 | 84 | 02:10 |
| Penonomé | 151 | 94 | 02:25 |
| Natá | 186 | 115 | 02:53 |
| Aguadulce | 197 | 122 | 03:01 |
| Divisa | 215 | 133 | 03:16 |
| Santa María | 218 | 136 | 03:20 |
| Parita | 240 | 149 | 03:40 |
| Pesé | 268 | 166 | 04:10 |
| Chitré | 252 | 157 | 03:50 |
| Los Santos | 256 | 159 | 03:55 |
| Guararé | 277 | 172 | 04:15 |
| Las Tablas | 282 | 175 | 04:20 |
| Pocrí | 303 | 190 | 04:50 |
| Pedasí | 324 | 203 | 05:20 |
| Ocú | 245 | 152 | 03:46 |
| Atalaya | 251 | 156 | 03:51 |
| Santiago | 250 | 155 | 04:25 |
| Soná | 296 | 184 | 05:15 |
| Tolé | 350 | 218 | 05:40 |
| Remedios | 391 | 243 | 06:25 |
| San Félix | 369 | 231 | 04:55 |
| San Lorenzo | 398 | 248 | 05:20 |
| David | 440 | 274 | 06:00 |
| Boquete | 480 | 299 | 06:45 |
| Concepción | 457 | 284 | 06:05 |
| Volcán | 498 | 309 | 06:55 |
| Cerro Punta | 514 | 319 | 07:15 |
| Puerto Armuelles | 530 | 330 | 07:07 |
| Frontera | 494 | 307 | 06:32 |
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- Road Distances from Panama City
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